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Image Search Results
Journal: JCI Insight
Article Title: The homozygous CX3CR1-M280 mutation impairs human monocyte survival
doi: 10.1172/jci.insight.95417
Figure Lengend Snippet: Shown are percent of dead monocytes elicited by serum starvation in the presence or absence of 100 nM of CX3CL1 after exposure to 50 μM of the PI3K inhibitor LY294002 (A, n = 5) or 20 μM of the MEK inhibitor PD98059 (B, n = 6), or 100 nM of the PI3K inhibitor wortmannin (C, n = 6) or 20 μM of the MEK inhibitor U0126 (D, n = 5). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. Statistical analysis was performed using 1-way ANOVA with Tukey’s multiple comparisons test. Data represent the mean ± SEM.
Article Snippet: Monocytes (1 x 10 5 ) were pretreated for 20 minutes at 37 o C with either the PI3K inhibitor {"type":"entrez-nucleotide","attrs":{"text":"LY294002","term_id":"1257998346","term_text":"LY294002"}} LY294002 (50 μM; Tocris Bioscience, catalog 1130) or the
Techniques: